I
Isomorphic Labs Drug Design Engine
PaidResearchResearch
The Isomorphic Labs Drug Design Engine (IsoDDE) is an AI system that moves beyond protein structure prediction into active drug design, achieving double the accuracy of AlphaFold 3 on complex structural predictions. Published in February 2026, it predicts binding affinity and identifies cryptic binding sites from just protein sequences, dramatically accelerating the drug discovery process from years to weeks.